Wow - its own Sub Forum

barbara

Pioneer Founding member
Dr. Feinerman's approach to the treatment of autism with stem cell therapy

Dr. Feinerman sent this to me a few weeks ago in response to a question I had concerning autism treatment. He also used to run a school for autistic children. This is obviously of great interest to him.




STEM CELL THERAPY AND AUTISM

Autism was first described by Dr. Leo Kanner in 1943 as a collection of symptoms with poor social engagement, limited verbal and nonverbal communications and repetitive behaviors. We are now aware of a variety variations in this disorder. Children with Asperger?s share a lot of these behaviors of those with more severe autism.

Patients with autism share common inflammatory abnormalities. With brain imaging one notes that the white matter which carries impulses between neurons is larger in children with autism. Neuroglial inflammation is noted in all children with autism. Neuroglia are a group of brain cells that are important in the brain?s immune response. The inflammatory reaction appears both in the early and late stages of the disease. The approach for treatment is to reduce the brain?s immunological response. At NIH they are testing patients with minocycline, an anti-inflammatory antibiotic drug on autistic children.

Autism involves behavior, cognition, sensorimotor, gastrointestinal, immune system and endocrine abnormalities.
Current recommendations are the use of glutathinone which s a strong anti-oxidant in removing toxins and is linked to the methylation pathway of the cell; a biochemical process that
regulates which genes are expressed thus abnormal methylation can cause disease. The pathway provides precursors to glutathinone and thus impairment leads to oxidative stress. Oxidative stress in some autistic children can be targeted by giving the following supplements that are key nutrients in the methylation pathway.



These include:
Folinic acid
Trimethylglycine
Methyl- B12
Glutathinone

To support mitochondrial function that produce the energy in brain cells and are the place where free radicals are produced that play a role in oxidative stress and produce ATP. When free radicals are high in the body glutathione is depleted. To best stabilize mitochondrial function the addition of the following nutrients will help:

Mitochondrial Energizer (from Life Extension)
DNA Repair (from Life Extension)
CoQ10 enzyme 50-100 mg.
Magnesium
Acetyl-L-carnitine 500 mg.
Glutathione

For further brain metabolism support:
Phosphotidylserine
L-Carnosine
Alpha Lipoic Acid 300 mg.
DMAE 250 mg.
Selenium 200 mg
Fish Oil with GLA
L-Theanine( found in green tea extract)
Stem Cell Enhancer (oral)

Diet: Gluten free(present in wheat and grains) and dairy products.

Hyperbaric oxygen: may be useful in some cases.
Chelation of any heavy metals that may be present and other toxins is an essential part of treatment.

Through the years many different causes of autism have been considered. These include genetic disturbances, heavy metal toxins, allergies, brain damage from pertussis and measles vaccines, brain damage from mercury preservative in the vaccines.

Currently the focus of attention is on an inflammatory process that damages the brain. The explosion of diagnosed cases in the past thirty years in children that appeared normal in the early months of life in terms of their development and then started having sings of autism suggests some exogenous source. The neuorinflammatory concept is now the most seriously considered.

Patients with autism are candidates for stem cell therapy. The stem cells which are pluripotent are extracted from umbilical cord blood placed into culture with specific growth factors and nutrients that can be programmed to produce brain stem cells as well as anti-inflammatory immune cells. The patients are infused with brain stem cells (astrocytes); neuron stem cells;
mesenchymal stem cells(20 million cells); oligodendrocytes (producing myelin) plus dendritic immunological cells with nerve growth factor; glial derived neurotrophin (which stimulates myelin production); brain neuropeptide; vascular endothelial growth factor. The stem cells are given intravenously using an agent so that the cells can penetrate the blood-brain barrier over a short period of time (or administered through a spinal tap- see below) The stem cells will home (migrate) only to the brain where they engraft at areas of damage, survive and proliferate only up to the point of repair and replacement.
An optional approach (whicwe recommend) is to give the neuron stem cells and growth factors directly into the central nervous system via the spinal canal. This procedure is safe and effective. Patients are given a local anesthesia and mild analgesia/sedation for about fifteen minutes to perform this technique. Parents after consultation with our medical staff and their own private physicians can make the choice of intravenous or spinal canal administration.
Post stem cell therapy will focus on continued healthy brain metabolism of the cells. Patient?s progress is followed by evaluations every three months. Recommended supplements post procedure are Vitamin B12, L-Carntine, Phosphotidylserine, Mitochondrial Energizer, DNA Repair and Cell Advance (a stem cell stimulant).
 

Jeannine

Pioneer Founding member
I have to add that the supplements Dr F recommends for Autism are available on our SeaChange site as he refers his patients to us for supplements.
 

pink7

New member
Autism

I am new here. I have a child with Autism. I have been thinking of doing stem cell treatment for my child. Is autologous or umbilical cord stem cells better for Autism?
Which clinics are good in treating Autism? I would appreciate some advice on stem cell treatment.

pink7
 

hegy

New member
autism

hi, and welcome to the forum,
if you click on search then type in autism then show posts, you will get lots of information on that condition.
I am sure that barbara and jeanine and others will be happy to point the way for you.
 

pink7

New member
Autism

hi, and welcome to the forum,
if you click on search then type in autism then show posts, you will get lots of information on that condition.
I am sure that barbara and jeanine and others will be happy to point the way for you.
Thanks. It was most helpful to read the posts .I need to research the best options for my child.

Pink7
 

barbara

Pioneer Founding member
If you need clinic website info or phone numbers, please let me know and I will send the resources that I have to you.
 

pink7

New member
Autism

If you need clinic website info or phone numbers, please let me know and I will send the resources that I have to you.
Thanks Barbara. Please send me the clinic website info and phone numbers and I will check them out. It would be most useful.

pink7
 

pink7

New member
Autism

Does anyone have any experience with stem cells being infused by the spinal method. I have a child with Autism and older children seem to do better when stem cells are infused using the spinal method. Recently there has been some warning about infusing stem cells using the spinal method for MS.
I was wondering whether there was any negative effects using this method. I would appreciate any advice on this.

pink7
 
Top