Has anyone tried filgrastim to restore pulmonary parenchyma and cure emphysema?

Vancouverman

New member
Hello,

In humans we use filgrastim (granulocyte colony-stimulating factor (G-CSF) ) to mobilize stem cells. Doctors also use it in donors who want to donate their stem cells to other recipients. No long-term risks have been found so far in filgrastim use.

Now, in a mouse model filgrastim recovers and completely repairs the emphysematous lung!

So I am wondering if anyone of you tried it? It is administered as a subcutaneous injection.

It is also very promising.

Recombinant Human Granulocyte Colony-Stimulating Factor Versus Bone Marrow Mononuclear Cells in Treatment of Pulmonary Emphysema Model



Recovery of pulmonary structure and exercise capacity by treatment
with granulocyte-colony stimulating factor (G-CSF) in a mouse model
of emphysema



Long-term safety of filgrastim (rhG-CSF) administration
 
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