Collaboration Strenghens

zar

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Collaboration Strengthens Ground-breaking UK Stem Cell Project

Gothenburg, Sweden and Cambridge, UK, Tuesday, August 29, 2006

Cellartis AB and NovaThera announce today further progress in developing platform technologies for regenerative medicine by forming a research partnership, utilizing the proprietary stem cell technology from Cellartis AB.
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NovaThera heads a large UK Department of Trade (DTI) programme to realise an ambitious plan to help overcome the challenges faced in the production of clinical grade stem cells in large quantities for medical trials. The scientific partners in the program include the centres of academic excellence in Imperial College London, Cambridge University, Manchester University and the Roslin Institute in Scotland.
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?If stem cell-based therapies are to be a readily affordable treatment, we must abandon the complex, time-consuming and expensive tailor made route. We need to scale up cell production and provide large amounts of clinical grade material for medical treatments?, said Gareth Roberts CEO of Novathera, who are focussed on turning stem cell science into medical applications for the treatment of chronic lung and heart disease.
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Cellartis will now contribute to the programme through the provision of its proprietary embryonic stem cell lines. ?We are delighted to access the wealth of know-how and expertise in the derivation and expansion of embryonic stem cell lines provided by Cellartis? said Dr Robert Daniels, CCO of NovaThera.
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?This very important collaboration is in line with our strategic goal of scaling up our human embryonic stem cell technology while leveraging the presence of our cells at top universities in the UK ? said Mats Lundwall, CEO of Cellartis.
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Under the terms of the agreement, NovaThera and Cellartis will jointly pursue commercial applications of the technologies arising from the research.

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Cellartis AB is one of the few companies in the world that is engaged in research, development and manufacture of human embryonic stem (hES) cells and specialised functional cells derived from these cell lines. The company is the world?s largest single source of defined hES cell lines, including cell lines derived under completely xeno-free conditions. Today the company has more than 30 stem cell lines available for research and has the capabilities, in line with appropriate legislative and ethical compliance requirements, to develop cells and applications for the discovery of new pharmaceuticals, regenerative medicines and toxicology. Two of the cell lines are listed in the National Institutes of Health (NIH) Human Embryonic Stem Cell Registry (www.nih.gov), and 20 of the cell lines are listed in the UK Stem Cell Bank (http://www.ukstemcellbank.co.uk/). The company was founded in 2001 and has the headquarters in state-of-the-art premises in the Biotech Centre, close to Sahlgrenska University Hospital, Gothenburg, Sweden.
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NovaThera Ltd specializes in pioneering applications of biomaterials and stem cell biology to provide innovative therapeutic solutions in regenerative medicine. NovaThera was originally spun-out from Imperial College London and now has close ties with six of the UK?s leading stem cell and biomaterial research groups. In addition, NovaThera has developed strategic corporate partnerships or licenses with corporations across Europe, the US and Asia. NovaThera has a strong pipeline of products, including a range of wound care products in late stage clinical trials, technology platforms for the scale up of stem cell production, and cell based respiratory products in late stage preclinical studies with both therapeutic and toxicity testing applications

Release date: 18/09/06
 

danny

New member
I have talked to the CEO of this company and they plan to start human trials in 2008 for lung diseases.
 

zar

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Gamida Cell and NovaTHera

Hi Danny,

Gamida Cell and NovaThera to collaborate on lung repair

May. 9, 2007
Source: Gali Weinreb, Globes
Israeli start-up Gamida Cell Ltd. And NovaThera Ltd. Of the UK have signed a cooperation agreement for the development of cell therapeutic treatments for lung repair and regeneration. The companies will pool technology and expertise and work together with the clinical team at Papworth Hospital in Cambridge towards advancing cell therapy approaches for treating lung disease.

Gamida Cell CEO Dr. Yael Margolin said, ?This collaboration is in line with our strategy to partner with selected companies focused on developing therapeutics for life threatening illnesses and to help bring these products to market.?

NovaThera, owned by London?s Imperial College, specializes in pioneering applications of biomaterials and stem cell biology for regenerative medicine and tissue engineering to provide innovative therapeutic solutions. Gamida Cell develops therapeutics using proprietary technologies that expand populations of hematopoietic stem/progenitor cells such as those derived from cord blood (not the controversial embryonic stem cells), for the treatment of hematological diseases as well as for tissue regeneration applications
 

zar

New member
NovaThera has been working with Dr. Sakis Mantalaris and Imperial College to explore collaborations with Chinese centres of excellence. ?Our initial contacts revealed a high level of scientific expertise and a willingness to commit to developing regenerative medical technologies,? said Dr. Mantalaris. ?Our programme of exchange visits made rapid progress in assessing technologies and plans for developing new therapeutic approaches?.

?Once the opportunity was identified, we worked with our partners at Eastway Consultants to develop the ideas into SteMing Asia and more importantly put the right management team and resources in place to drive the business forward,? said Dr. Rob Daniels, CCD of NovaThera.

SteMing Asia is positioned as a central player in the delivery of cell based therapies in China and Asia. A team with European, US, and Chinese management experience leads the JV Company, which is a consortium of partners with an extensive local network, including R&D based at the Hong Kong University of Science and Technology, cGMP production facilities, and clinical application and development partnerships with hospitals throughout China. ?SteMing Asia was established to be the partner of choice for NovaThera -- and other cell therapy companies -- to access China and Asia?s market,? said Dr. Ming Pang, Chairman of SteMing Asia.

The company?s near term activities draw on NovaThera?s proprietary 3-D cell culture technology and will include the expansion of umbilical cord blood cells for therapeutic application as well as sales of a bioreactor for culturing human embryonic stem cells (hES) for research purposes. Additionally, SteMing Asia will have an exclusive option to access all platform technologies and novel IP protected regenerative products developed by NovaThera Ltd for the ASEAN region. NovaThera continues to develop and access innovations in regenerative medicine through collaborations with Imperial College, one of the world?s leading research centres in this area and with five other leading academic stem cell research groups in the UK (Cambridge, Southampton, Manchester, Cardiff and the Roslin Institute). ?This provides a significant opportunity to build a business in China that can continue to access some of the best science and technology in the world,? said Dr. Pang.

The Chinese Ambassador His Excellency Mr Zha Peixin and Counsellor Zhang
 

zar

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SteMing Asia Ltd (?SteMing Asia?) is a joint venture between NovaThera (Asia) Ltd (?NTAL?) (a wholly owned subsidiary of NovaThera Ltd), and a consortium of partners in Asia, including Hong Kong University of Science and Technology (HKUST), Eastway Consultants Ltd., and a network of Chinese clinicians, angel investors, and business development partners. SteMing Asia will commercialise cell therapeutics and cell services in China and ASEAN initially. For more information on SteMing Asia contact clara.shen@stemingasia.com SteMing Asia Ltd.,Rm 4599, 4/F, Annex, University of Science and Technology Clear Water Bay, Kowloon, Hong Kong tel: +852 2358 4865; fax: +842 2358 4931; hp: +852 6681 0710

Background on Eastway Consultants Ltd.

Eastway Consultants Ltd (?Eastway Consultants?) is based in Hong Kong with a team of senior executives from multinational pharmaceutical companies. Eastway Consultants provides integrated services for the pharmaceutical, biotechnology and healthcare industries. Specialising in Technology Transfer & Management, International Regulatory & Compliance, Facilities Services & Plant Design, Marketing & Distribution Partnership and Strategic Alliances & Fund Raising.

Would the trials be held in Hong Kong?
zar
 
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