The Lancet, Volume 349, Issue 9066, Page 1675, 7 June 1997
Retinoic acid reverses emphysema in rat model
Original TextMichael McCarthy
All- trans retinoic acid (RA), a vitamin A derivative, reverses emphysema in an animal model of the disease, report US researchers ( Nat Med 1997; 3 : 675?77). ?This is the first time that anyone has identified a means of reversing emphysema?, says Claude Lenfant, director of the US National Heart, Lung, and Blood Institute. ?It could lead to the development of an agent for treating lung diseases like emphysema and bronchopulmonary dysplasia.?