Regular consumption of spicy foods may increase lifespan

barbara

Pioneer Founding member
Medical News Today
8-5-15

Spicy food can make you feel like your mouth is on fire and cause you to sweat profusely. However, a new study suggests that regularly eating spicy food could also lower the risk of death from specific conditions.

Fresh chilis contain capsaicin, which has been reported to have anticancer, anti-inflammatory and antihypertensive effects.
The observational study, published in The BMJ, found people whose daily diets regularly featured spicy foods had a lower risk of death from cancer, ischemic heart disease and respiratory disease.

Many previous studies have demonstrated health benefits for spices such as red pepper, and others have demonstrated that certain bioactive agents in spices such as capsaicin can have beneficial effects in conditions such as obesity and cardiovascular disease.

While these studies suggest that spices could play a prominent role in human health, there is currently a lack of evidence for the effects of daily spicy food consumption on disease-specific and all-cause mortality from population studies.

To address this, a research team led by researchers from the Chinese Academy of Medical Sciences analyzed data obtained from the China Kadoorie Biobank - a prospective cohort study of more than half a million adults from geographically diverse regions in China.

They followed a total of 487,375 participants aged between 30 and 79 who were regularly assessed for illness. When each participant was enrolled to the study between 2004-2008, they completed a questionnaire about their health and consumption of spicy foods, red meat, vegetables and alcohol.

During the follow-up period, 5% of surviving participants were randomly surveyed again in 2008 to assess whether the baseline questionnaire results accurately reflected spicy food consumption over time. The study authors report these questionnaires indicated that spicy food consumption was reported consistently.

A total of 20,224 deaths were recorded during the follow-up period, with participants tracked for an average of 7.2 years.

Frequent consumption of spicy food linked to 14% reduced risk of death during follow-up
The researchers observed that participants who reported eating spicy foods 3-7 days a week were 14% less likely to have died than participants who ate spicy foods less than once a week. Participants who ate spicy foods once or twice a week were at a 10% reduced risk of dying compared with participants who ate spicy foods less than once a week.

Frequent consumption of spicy foods was also associated with a lower risk of death from cancer, ischemic heart disease and respiratory system diseases. This reduced risk was more prominent among female participants than male participants.

In terms of spicy food, the researchers found that the most commonly used spices for participants who ate spicy foods weekly were fresh and dried chili peppers. Participants who regularly ate fresh chili had a reduced risk of death from cancer, ischemic heart disease and diabetes.

"Possible mechanisms might involve the bioaccessibility and bioavailability of bioactive ingredients and nutrients of spicy foods," the authors write, "but further studies are needed to verify our findings."

The authors caution that because the study was an observational one, causal inferences should not be made and further prospective studies should be conducted to demonstrate the generalizability of their findings.

In an accompanying editorial, Nita G. Forouhi, of the Epidemiology Unit at the University of Cambridge in the UK, writes that a systematic appraisal of the potential benefits and adverse effects of spicy foods is warranted.

"Should people eat spicy food? It is too early to say, but the debate and the research interest are certainly hotting up," she concludes.

Last month, Medical News Today reported on analysis conducted by the Centers for Disease Control and Prevention (CDC) that found only 13.1% of American adults eat enough fruits and only 8.9% eat enough vegetables.

Fast facts about capsaicin
Native Americans have used cayenne pepper as a form of medication for at least 9,000 years
Capsaicin can be found in many over-the-counter medicines for pain relief
Capsaicin is also an ingredient in many forms of pepper spray.

Written by James McIntosh
 

barbara

Pioneer Founding member
Respiratory diseases benefit too

This article also mentions benefits for respiratory diseases.

A Chili Pepper A Day Keeps Mortality Away, Chinese Scientists Say
08/05/2015
Seth Augenstein, Digital Reporter
Laboratory Equipment

Spicy food could help adventurous eaters maintain a healthy weight, control gut bacteria and even potentially reduce the risk of cancer, according to a series of studies. But it could simply stave off death, according to a massive new Chinese population study published in the British Medical Journal.

The mortality rate among regular eaters of chili pepper was less than those who did not partake of the spicy ingredient, according to the research, led by doctors at the Peking University Health Science Center.

Nearly 500,000 people in China from all over the country were analyzed for their spice-eating habits, as well as their health outcomes, over a median timeframe of 7.2 years. Age, smoking, obesity and other factors were adjusted so the comparison between spice eaters and non-spice eaters was direct.

“Our findings are in line with previous evidence showing potential protective effects of spicy foods on human health,” they concluded.

The mortality rate for people who ate spicy foods six or seven days a week (5.8 deaths per 1,000 person-years) was lower than those who ate spicy foods less than once a week (6.1 deaths per 1,000 person-years). But the best results were those who ate spicy foods at moderate intervals: one or two days a week (4.4 deaths) and three to five days per week (4.3 deaths).

The Chinese team pointed to a particularly reduced risk of mortality because of cancer, ischemic heart diseases and respiratory diseases among the 3.5 million person-years they evaluated.

The cause is not clear – but there are guesses. The active ingredient in chili, capsaicin, could be behind the improved mortality rates – since a drumbeat of studies have shown it to have a wide variety of helpful effects, they concluded.

“The beneficial roles of capsaicin have been extensively reported in relation to anti-obesity, antioxidant, anti-inflammatory, anticancer and antihypertensive effects and in improving glucose homeostasis, largely in experimental or small size population studies. Additional, the antimicrobial function of spices, including chili pepper, has long been recognized and such a property may have an important effect on the gut microbiota in humans.”

An accompanying analysis in the BMJ found the “novel findings” were intriguing, but needed follow-up investigation.

“So, should we encourage people to eat more chili?” wrote Nita Forouhi, of the University of Cambridge School of Clinical Medicine. “Future research is needed to establish whether spicy food consumption has the potential to improve health and reduce mortality directly or if it is merely a marker of other dietary and lifestyle factors.”

A 2013 study in the European Journal of Pharmacology found capsaicin’s positive effects might be because of a nullifying effect is has on a specific receptor in neurons. But the study said much more work to pinpoint the effects in human models was required.

However, not all the news is good. A study published last December by some of the same Chinese researchers indicated that spicy foods might actually be a risk factor for obesity among men in certain populations.
 
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