oesophageal candidiasis (OC)

zar

New member
This article reviews risk factors, prevention and management of oesophageal candidiasis (OC) in the elderly. Putative risk factors for OC in the elderly include old age itself, malignant disease, antibacterial and corticosteroid use, chronic obstructive pulmonary disease, acid suppression treatment, oesophageal dysmotility and other local factors, diabetes mellitus and HIV/AIDS. We have found evidence for a risk association between OC in the elderly and malignant disease (both haematological and non-haematological), antibacterial therapy and corticosteroid (including inhaled corticosteroids) use. We also found evidence of an association between OC in the elderly and oesophageal dysmotility or HIV/AIDS, but little direct evidence of an association between diabetes or old age per se. The literature on OC in the elderly is not large. The published series evaluating OC in this age group are small in size, often do not contain controls and mostly contain only limited information about the age of the patients. Prevention of OC is mainly the avoidance of exposure to the risk factors wherever possible. Specific measures such as highly active antiretroviral therapy in AIDS, prophylactic fluconazole when receiving chemotherapy for malignancy, using spacing devices, mouth rinsing soon after inhalation of corticosteroids and avoiding the use of cortiocosteroids just before bedtime are useful. OC is often responsive to a 2- to 3-week course of oral fluconazole, but resistance may be encountered in AIDS or in the presence of uncorrected anatomical factors in the oesophagus. Itraconazole solution, voriconazole or caspofungin may be used in refractory cases. Use of amphotericin B is restricted because of its narrow therapeutic index. http://www.ncbi.nlm.nih.gov/pubmed/18257599?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
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Fluconazole or Itraconazole http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=meds&log$=drug_bottom_one&part=a690002
 

Jeannine

Pioneer Founding member
Zar

Many of us with COPD suffer with Candida (mouth thrush) due to the inhalers we use (Advair being the most common culprit). Many of us have found that rinsing our mouths and gargling with colloidal silver for a few days keeps this under control.
 

Mysty119

New member
Does anyone using Advair, tend to lose their voice at times? Not totally loose it, but your voice is certainly diminished.
 

zar

New member
Does anyone using Advair, tend to lose their voice at times? Not totally loose it, but your voice is certainly diminished.
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Ask your Doctor about giving you two seperate inhalers.
One fluticasone and one salmeterol so you can reduce one puff of steroid per day(with you Doctor knowing),that will reduce a lot of side effects.
 
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