Hello Barbara. I am very sorry to hear about your mother's passing. My deepest condolences. I've read the first installment of Dr. Bill's answers posted by Jeannine. I will ask the next doctors about the bio-identical hormones. Other women got together on Oprah, doctors even and said it was perferctly safe and natural. Anyway, take care and wishing you and everyone on the forum a better and happier, healthier new year.